Pharmacies in 12 regions (autonomous communities) carried out more than one million COVID tests (1,043,801) and reported 109,569 positives up to 15 February, since July 2021, when the dispensation of self-diagnostic tests for COVID-19 was authorised without prescription. Since then, we have started to collaborate with different health authorities in the supervision, implementation and notification of positive tests, reaching 12 Autonomous Communities in which 27 million citizens reside. In 2022 alone, coinciding with the sixth wave, pharmacies performed or supervised more than 600,000 tests and notified the National Health System (NHS) of more than 82,000 positive results.